Genetic dating

Here, we estimate recombination breakpoints in admixed genomes based on genome-wide SNP data and date the genetic admixture between populations of Asian vs. Analyses of two genome-wide datasets indicate an eastward progression of the Asian admixture signal in Eastern Indonesia beginning about 4,000–3,000 y ago, which is in excellent agreement with inferences based on Austronesian languages.

The average rate of spread of Asian genes in Eastern Indonesia was about 0.9 km/y.

Well, now that a computer app can take the raw data of our Cs and Gs and Ts and As and spit out a single number—the polygenic score—that predicts (with error, of course) someone’s height or risk for cognitive decline, would you like to know whether the person who just proposed to you is a walking genetic time bomb?

We have always selected our mates for their phenotypes—outwardly observable characteristics—that are driven partly by genetics and partly by environment.

People who have the short version of this gene tend to respond more emotionally to negative and positive situations, while people with the long version of the gene tend to be more levelheaded.

What they found is if you have two married individuals who both share the short version of the gene, what you get is a level of affection that goes down over time.

We have all the research that has been done on couples looking for biomarkers that can determine compatibility and why certain couples do better than others, and so we launched [Instant Chemistry] based on that, and started working with premium matchmakers, giving out kits.

There are some really interesting studies from UC Berkeley where they looked at couples who were in a relationship for 10 years.

This process is often termed the Austronesian expansion, which represents a complex demographic process of interaction between migrating Neolithic farmers and indigenous Mesolithic hunter–gatherer communities, a frequent phenomenon in world prehistory.

However, our knowledge about the historical origin and spread of Austronesian-speaking peoples has been overwhelmingly from linguistic, archaeological, and anthropological studies (1).

Now that we can somewhat measure their genotypes—the actual stuff that a baby daddy passes on to junior—it is inevitable that discerning potential partners will demand their counterparts show their cards before committing.

Even if you landed a man or woman with advanced degrees, would it give you pause if you learned that he or she was genetically likely to develop early dementia and, worse, pass that risk onto your offspring?

But another technology is afoot that few people know about but that will upend the way we match and reproduce in years to come: the polygenic score.

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